Molecular allergy diagnosis: Status anno 2015

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Molecular allergy diagnosis: status anno 2015.

IgE antibodies play a key role in type I allergic reactions. Today, different in vitro immunoassays for allergen-specific IgE antibodies are available. However, some major issues should be taken into account for correct interpretation of specific IgE (sIgE) antibody results, as these assays do not demonstrate absolute positive and negative predictive values. Therefore, additional diagnostic tes...

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PURPOSE OF REVIEW Allergy to hen's egg is common in infancy and childhood. Oral food challenges are often required to diagnose egg allergy, because of the limitation in the diagnostic accuracy of skin test and specific IgE to egg white. New molecular diagnostic technologies have been recently introduced into allergological research. In this article, we will review the recent literature regardin...

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PURPOSE OF REVIEW The purpose of this paper is to review and discuss studies on molecular diagnosis in fruit and vegetable allergy. RECENT FINDINGS Celeriac, carrot and tomato are the most prevalent allergenic vegetables, whereas fruit allergy is mainly induced by apple, peach and kiwi. Component-resolved molecular diagnosis has been recently applied in two well-defined patient groups with ki...

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Molecular Approach to Allergy Diagnosis and Therapy

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ژورنال

عنوان ژورنال: Clinica Chimica Acta

سال: 2015

ISSN: 0009-8981

DOI: 10.1016/j.cca.2015.02.012